Emile Van Schaftingen Selected Research

phosphoglycolate

1/2019

Phosphoglycolate has profound metabolic effects but most likely no role in a metabolic DNA response in cancer cell lines.

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Emile Van Schaftingen Research Topics

Disease

5	2-Hydroxyglutaricaciduria 01/2020 - 11/2004
4	Neutropenia 01/2022 - 01/2019
4	Neoplasms (Cancer) 01/2019 - 09/2009
3	Congenital Disorders of Glycosylation 10/2013 - 07/2012
2	Neurodevelopmental Disorders 01/2022 - 01/2021
2	Glycogen Storage Disease (Glycogenosis) 01/2020 - 01/2020
2	Leukoencephalopathies 01/2019 - 05/2013
2	Seizures (Absence Seizure) 07/2012 - 05/2007
1	NGLY1 deficiency 01/2022
1	Parkinson Disease (Parkinson's Disease) 01/2022
1	Infections 01/2022
1	Congenital, Hereditary, and Neonatal Diseases and Abnormalities (Congenital Disorders) 03/2021
1	Short chain Acyl CoA dehydrogenase deficiency 01/2021
1	Glycogen Storage Disease IB 01/2020
1	Rare Diseases (Rare Disease) 01/2020
1	Type 2 Diabetes Mellitus (MODY) 01/2020
1	Hypoglycemia (Reactive Hypoglycemia) 01/2020
1	Brucellosis (Malta Fever) 01/2017
1	Brain Diseases (Brain Disorder) 01/2016
1	Inborn Errors Metabolism (Inborn Errors of Metabolism) 07/2015
1	Alacrima 10/2013
1	Esophageal Achalasia (Megaesophagus) 10/2013
1	Limb-Girdle Muscular Dystrophies (Limb-Girdle Muscular Dystrophy) 10/2013
1	Polyneuropathies (Polyneuropathy) 07/2012
1	Cataract (Cataracts) 07/2012
1	Schizophrenia (Dementia Praecox) 03/2012
1	Bipolar Disorder (Manic Depressive Psychosis) 03/2012
1	Dehydration (Water Stress) 12/2011
1	Urinary Tract Infections (Urinary Tract Infection) 09/2008
1	Microcephaly 05/2007
1	Ascorbic Acid Deficiency (Vitamin C Deficiency) 01/2007

Drug/Important Bio-Agent (IBA)

8	EnzymesIBA 01/2022 - 09/2008
6	Proteins (Proteins, Gene)FDA Link 01/2022 - 11/2004
4	Oxidoreductases (Dehydrogenase)IBA 01/2015 - 11/2004
3	Glucose-6-PhosphateIBA 01/2022 - 01/2019
2	empagliflozinIBA 01/2022 - 01/2020
2	Sodium-Glucose Transporter 2 InhibitorsIBA 01/2022 - 01/2020
2	1,5-anhydroglucitol-6-phosphateIBA 01/2022 - 01/2020
2	Glucose-6-Phosphatase (Glucose 6 Phosphatase)IBA 01/2020 - 01/2019
2	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 01/2019
2	AcidsIBA 01/2019 - 11/2004
2	Dystroglycans (Dystroglycan)IBA 01/2016 - 10/2013
2	Serine (L-Serine)FDA Link 07/2012 - 05/2007
1	polyolIBA 01/2022
1	HexokinaseIBA 01/2022
1	1,5-anhydroglucitolIBA 01/2022
1	OligosaccharidesIBA 01/2022
1	glucose-1,6-bisphosphateIBA 01/2021
1	ethylmalonic acid (ethylmalonate)IBA 01/2021
1	Butyryl-CoA Dehydrogenase (Short-Chain Acyl-CoA Dehydrogenase)IBA 01/2021
1	SugarsIBA 01/2021
1	NADP (NADPH)IBA 01/2020
1	NAD (NADH)IBA 01/2020
1	Hypoglycemic Agents (Hypoglycemics)IBA 01/2020
1	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 01/2020
1	Sodium-Glucose Transport ProteinsIBA 01/2020
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2019
1	phosphoglycolateIBA 01/2019
1	DNA (Deoxyribonucleic Acid)IBA 01/2019
1	nitrilaseIBA 01/2017
1	ErythritolIBA 01/2017
1	Aldehyde Reductase (Aldose Reductase)IBA 01/2017
1	Nonsense Codon (Nonsense Mutation)IBA 10/2013
1	Guanosine Diphosphate (GDP)IBA 10/2013
1	Polysaccharides (Glycans)IBA 10/2013
1	Glycoproteins (Glycoprotein)IBA 10/2013
1	Guanosine Diphosphate Mannose (GDP Mannose)IBA 10/2013
1	GlycolipidsIBA 10/2013
1	mannose 1-phosphate guanylyltransferaseIBA 10/2013
1	Transferrin (beta 2 Transferrin)IBA 07/2012
1	Amino Acids FDA Link 07/2012
1	Phosphoglycerate Dehydrogenase (Dehydrogenase, Phosphoglycerate)IBA 07/2012
1	phosphorylethanolamine (phosphoethanolamine)IBA 03/2012
1	Adenosine Triphosphate (ATP)IBA 12/2011
1	Hydro-Lyases (Dehydratases)IBA 12/2011
1	Adenosine Diphosphate (ADP)IBA 12/2011
1	6-hydroxy-1,4,5,6-tetrahydronicotinamide adenine dinucleotideIBA 12/2011
1	NucleotidesIBA 12/2011
1	Transaminases (Aminotransferases)IBA 09/2009
1	omega-amidaseIBA 09/2009
1	Glutamine (L-Glutamine)FDA Link 09/2009
1	PseudouridineIBA 09/2008
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 05/2007
1	gulonolactoneIBA 01/2007
1	gulonic acid (gulonate)IBA 01/2007
1	alpha-hydroxyglutarateIBA 02/2005
1	Ketoglutaric Acids (Ketoglutaric Acid)IBA 11/2004
1	Flavin-Adenine Dinucleotide (FAD)IBA 11/2004

Therapy/Procedure

1	Off-Label Use 01/2020